Abstract

( Hp ) infection, responsible for elevated gastric cancer mortality in the region. A key concern is poor effectiveness of anti- Hp treatment. uninsured survivors had high risk of forgoing care. Additional ad- justment for chronic health conditions did not alter these results. Conclusions: The findings of this study show that provision of public insurance to all childhood cancer survivors may diminish racial/eth-nic disparities in forgoing care that exist among the privately-insured and reduce the risk of forgoing care among uninsured survi- vors to that of privately-insured non-Hispanic/Latinx Whites. Key messages: Providing publicly funded health insurance coverage to childhood cancer survivors can reduce disparities in forgoing medical care. Abstract 842 Background: Chronic hypertension is a strong risk factor for severe preeclampsia/eclampsia (SPE), and timely obstetric intervention can prevent SPE and reduce perinatal complications. We quantified ges- tational age-specific rates of SPE and estimated the benefits of preventive interventions among women with chronic hypertension at term gestation ( (cid:2) 37 weeks). Methods: Women with chronic hypertension and a term, singleton, hospital delivery in Washington State, 2003-2013, were included in the study (N ¼ 9697) with data obtained from birth certificates and hospital records. Adverse outcomes included SPE and composite se- vere neonatal morbidity (e.g., seizures, intracranial hemorrhage) and perinatal death (SNMM). Preventive interventions included labour induction and pre-labour cesarean delivery. Results: There were 1026 cases of SPE (10.6 per 100 women with chronic hypertension). Gestational age-specific SPE rates ranged be- tween 2.8 and 4.1 per 100 ongoing pregnancies; the frequency of preventive intervention at each gestational week ranged between 58% and 66%. Gestational age-specific SPE and SNMM rates were lower following preventive intervention: such intervention reduced the frequency of SPE/SNMM by 28 per 100 additional interventions at 37 weeks, 22 per 100 at 38 weeks, 17 per 100 at 39 weeks, 13 at 40 weeks and 6 per 100 additional interventions at 41 weeks’ gestation. Conclusions: Labour induction and pre-labour cesarean delivery at term gestation can prevent a substantial proportion of severe pre-eclampsia/eclampsia and perinatal death/severe neonatal morbidity among women with chronic hypertension. Key messages: SPE occurs in approximately 11% of women with chronic hypertension at term gestation. Obstetric interventions can prevent SPE and improve adverse pregnancy outcomes.