Emerging insights in the management of hemoglobin E beta thalassemia


Journal article


Nancy F Olivieri, Vivekanandan Thayalsuthan, Angela O’Donnell, Anuja Premawardhena, Christopher Rigobon, Giulia M Muraca, Cristopher Fisher, David J Weatherall
Annals of the New York Academy of Sciences, vol. 1202, 2010, pp. 155-7


Semantic Scholar DOI PubMed
Cite

Cite

APA   Click to copy
Olivieri, N. F., Thayalsuthan, V., O’Donnell, A., Premawardhena, A., Rigobon, C., Muraca, G. M., … Weatherall, D. J. (2010). Emerging insights in the management of hemoglobin E beta thalassemia. Annals of the New York Academy of Sciences, 1202, 155–157. https://doi.org/10.1111/j.1749-6632.2010.05579.x


Chicago/Turabian   Click to copy
Olivieri, Nancy F, Vivekanandan Thayalsuthan, Angela O’Donnell, Anuja Premawardhena, Christopher Rigobon, Giulia M Muraca, Cristopher Fisher, and David J Weatherall. “Emerging Insights in the Management of Hemoglobin E Beta Thalassemia.” Annals of the New York Academy of Sciences 1202 (2010): 155–7.


MLA   Click to copy
Olivieri, Nancy F., et al. “Emerging Insights in the Management of Hemoglobin E Beta Thalassemia.” Annals of the New York Academy of Sciences, vol. 1202, 2010, pp. 155–57, doi:10.1111/j.1749-6632.2010.05579.x.


BibTeX   Click to copy

@article{nancy2010a,
  title = {Emerging insights in the management of hemoglobin E beta thalassemia},
  year = {2010},
  journal = {Annals of the New York Academy of Sciences},
  pages = {155-7},
  volume = {1202},
  doi = {10.1111/j.1749-6632.2010.05579.x},
  author = {Olivieri, Nancy F and Thayalsuthan, Vivekanandan and O’Donnell, Angela and Premawardhena, Anuja and Rigobon, Christopher and Muraca, Giulia M and Fisher, Cristopher and Weatherall, David J}
}

Abstract

Globally, hemoglobin (Hb) E β thalassemia accounts for approximately half the severe forms of β thalassemia. Because of its wide clinical diversity and the ability of patients with this condition to adapt unusually well to low hemoglobin levels, the management of Hb E β thalassemia, particularly the decision to instigate regular blood transfusion, is particularly difficult. Here, we present a summary of our work in patients with this condition, which attempts to define clinical, adaptive, and genetic factors of possible value in determining the early management of this condition.